5-cnac as oral delivery agent for parathyroid hormone fragments
OwnerMoise Azria, Simon David Batemaninventors
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Abstract
Pharmaceutical compositions for the effective oral delivery of a parathyroid hormone, PTH, as well as methods for administration of the compositions are provided. Additionally, methods for stimulating new bone formation and treating and/or preventing osteoporosis are also provided.
Claims5
1-21. (canceled)
A pharmaceutical composition for oral delivery comprising recombinant PTH (1-34) and N-(5-chlorosalicyloyl)-8-aminocaprylic acid (5-CNAC) disodium salt.
A method for orally administering an effective dose of PTH comprising orally administering to a patient in need of PTH a pharmaceutical composition comprising recombinant PTH (1-34) and 5-CNAC disodium salt.
A method of stimulating new bone formation comprising orally administering to a patient in need of new bone formation a pharmaceutical composition comprising a therapeutically effective amount of recombinant PTH (1-34) and 5-CNAC disodium salt.
A method of treating osteoporosis comprising orally administering to a patient in need of said treatment a pharmaceutical composition comprising a therapeutically effective amount of recombinant PTH (1-34) and 5-CNAC disodium salt.
Dependencies are inferred from the claim text.