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US 2009/0263358 A1Published application
Method for treating multiple myeloma
AssigneeImmune System Therapeutics Ltd
InventorsROBERT LINDSAY RAISON, Rosanne Dorothy Dunn, Boon Hwa Andre Choo
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Abstract
The present invention relates to methods for the treatment of multiple myeloma. More particularly, the present invention relates to a method for inducing apoptosis in myeloma cells by administration of a K121-like antibody.
Claims14
-3. (canceled)
A method for autologous hematopoietic cell transplantation in a subject, the method comprising:
- (i) removing a hematopoietic progenitor cell population from the subject,
- (ii) treating the cell population with an antibody, and
- (iii) transplanting the treated cell population from step (ii) into the subject,
- wherein the antibody is not conjugated to a toxin or a cytolytic agent, and wherein the antibody comprises a VH region set forth in SEQ ID NO:1 and a VL region set forth in SEQ ID NO:3 or binds the same epitope of kappa myeloma antigen (KMA) as an antibody comprising a VH region set forth in SEQ ID NO:1 and a VL region set forth in SEQ ID NO:3.
1 more element
-9. (canceled)
(canceled)
Dependencies are inferred from the claim text.