A method for preventing and/or therapeutically treating a disease for which vascularization should be inhibited, comprising a step of administering one or more compositions selected from the group consisting of a husked but unpurified barley ethyl alcohol extract fraction, a husked but unpurified barley alkali extract fraction, a non-adsorbed fraction of a residual solution from the distillation of barley distilled spirits, which is not adsorbed with a synthetic adsorbent, an adsorbed fraction of a residual solution from the distillation of barley distilled spirits, which is adsorbed with a synthetic adsorbent, a fraction of a residual solution from the distillation of barley distilled spirits, which is precipitated with ethanol, and a lactic acid bacterium culture obtained by culturing a lactic acid bacterium in a culture medium containing a residual solution from the distillation of barley distilled spirits, to a patient afflicted with a disease for which vascularization should be inhibited.