Gas-filled microvesicles with polymer-modified lipids
AssigneeBracco Research S.A.
InventorsStephane Gorgerat, Christian Guillot, Feng Yan
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Abstract
Image enhancing contrast agents for use in diagnostic and/or therapeutic methods, particularly in the form of gas-filled microvesicles, with enhanced stability. The gas-filled microvesicles are stabilized by a layer of amphiphilic material and comprise from 0.15% to 1.0% by moles of a lipid bearing a hydrophilic polymer. The lipid bearing a hydrophilic polymer is preferably a phospholipid linked to polyethyleneglycol.
Claims10
Aqueous suspension of gas-filled microvesicles comprising an amphiphilic material, wherein said suspension further comprises from 0.15% by moles to 1% by moles of a lipid bearing a hydrophilic polymer.
Dependencies are inferred from the claim text.