Mucosally non-irritative amphotericin b formulations and methods for treating non-invasive fungus-induced mucositis
AssigneeAccentia Biopharmaceuticals, Inc.
InventorsFRANCIS E. O'DONNELL, JR., Donald Deroo
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Abstract
The present invention is directed to compositions and methods for non-irritatively treating and preventing non-invasive fungus-induced mucositis. Specifically, the invention involves compositions including a mucosally non-irritative mixture of amphotericin B and a pharmaceutically acceptable carrier. Such compositions can be non-irritatively mucoadministered to prevent, reduce, or eliminate chronic non-invasive fungus-induced mucositis conditions.
Claims29
A composition for mucoadministration comprising:
- a mucosally non-irritative mixture of amphotericin B and a pharmaceutically acceptable carrier.
A method of treating a subject having non-invasive fungus-induced mucositis, comprising mucoadministering an effective amount of a composition to the subject, wherein the composition comprises a mucosally non-irritative mixture of amphotericin B and a pharmaceutically acceptable carrier.
A method for reducing eosinophil in a subject comprising:
- non-irritatively mucoadministering a composition comprising an effective amount of amphotericin B and a pharmaceutically acceptable carrier.
A method for reducing the amount of major basic protein in the mucosa of a subject comprising:
- non-irritatively mucoadministering a composition comprising an effective amount of amphotericin B and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.