METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA
AssigneeNorchip A/S
InventorFrank Karlsen
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Abstract
An in vitro method is provided for screening human female subjects to assess their risk of developing cervical carcinoma which comprises screening the subject for expression of mRNA transcripts from the E6 and optionally the L1 gene of human papillomavirus, wherein subjects positive for expression of L1 and/or E6 mRNA are scored as being at risk of developing cervical carcinoma. Kits for carrying out such methods are also provided.
Claims8
A kit for use in the detection of mRNA transcripts from the E6 gene(s) of HPV, the kit containing primer-pairs which enable amplification of a region of E6 mRNA transcripts of HPV types 16, 18, 31, and 33, characterised in that the kit contains separate primer-pairs specific for E6 mRNA of each of the HPV types 16, 18, 31 and 33.
Dependencies are inferred from the claim text.