Application of a reagent to a matrix material
AssigneeOrion Diagnostica Oy
InventorsVeli-Mies Haiva, Anna Kaisa Kylma, Juhani Luotola
Life of this patent
Estimating the term…
Abstract
A reagent or particles having reagent supported thereon are applied to a matrix material by a contact printing process for example in which the matrix material is brought into contact with a rotating contact roll having the reagent or particles having reagent supported thereon disposed thereon so as to transfer the reagent or particles having reagent supported thereon to the matrix material. Such a contact printing processes allow high speed and high volume production of an assay device.
Claims59
-31. (canceled)
A test device for wiping over a surface to extract a sample, the test device comprising:
- two impermeable layers;
- and
- a layer of absorbent matrix material arranged between the impermeable layers,
- the matrix material carrying a reagent, and
- one of the impermeable layers having a plurality of openings aligned with the matrix material and through which a sample may be absorbed into the matrix material from a surface.
(canceled)
(canceled)
(canceled)
A test device for wiping over a surface to extract a sample, the test device comprising:
- two impermeable layers;
- a layer of absorbent matrix material arranged between the impermeable layers, the matrix material having a reagent applied thereto, one of the impermeable layers having at least one opening aligned with the matrix material and through which a sample may be absorbed into the matrix material from a surface;
- and
- a semi-permeable layer extending across the at least one opening, the semi-permeable layer being made of a semi-permeable material which allows a sample to pass therethrough whilst limiting backflow of the reagent from the matrix material.
(canceled)
-50. (canceled)
(canceled)
A method of extracting a sample from a surface comprising:
- providing a test device comprising:
- two impermeable layers, and
- a layer of absorbent matrix material arranged between the impermeable layers,
- the matrix material carrying a reagent, and
- one of the impermeable layers having a plurality of openings aligned with the matrix material;
- and
- wiping the surface with test device to absorb a sample into the matrix material from the surface through the openings.
A method of extracting a sample from a surface comprising:
- providing a test device for wiping over a surface to extract a sample, the test device comprising:
- two impermeable layers;
- a layer of absorbent matrix material arranged between the impermeable layers, the matrix material having a reagent applied thereto, one of the impermeable layers having at least one opening aligned with the matrix material;
- and
- a semi-permeable layer extending across the at least one opening, the semi-permeable layer being made of a semi-permeable material which allows a sample to pass therethrough whilst limiting backflow of the reagent from the matrix material;
- and
- wiping the surface with test device to absorb a sample into the matrix material from the surface through the at least one opening.
A method of manufacturing a test device for wiping over a surface to extract a sample, the method comprising:
- applying a reagent or particles having reagent supported thereon to an absorbent matrix material, the method comprising printing the reagent or particles onto the matrix material by bringing a contact roll having disposed thereon the reagent or the particles having reagent supported thereon into contact with the matrix material while the contact roll is rotated and the contact roll and the matrix material are relatively moved;
- laminating the matrix material between two impermeable layers, one of the impermeable layers having at least one opening aligned with the matrix material and through which a sample may be absorbed into the matrix material from a surface.
Dependencies are inferred from the claim text.