Method of preparing micro-and nanometric particles with labile Products
OwnerMiguel Alfonso Ganan Calvo, Sebastien Chavez De Diego +3inventors
InventorsMiguel Alfonso Ganan Calvo, Sebastien Chavez De Diego, Angel Cebolla Ramirez, Maria Flores Mosquera, Elena De Castro Hernandez
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Abstract
The invention relates to a method of obtaining micro- and nanometric polymeric particles in a controlled, reproducible manner. The aforementioned particles have a spherical shape and a very narrow, uniform size distribution. The invention comprises the use of an easy particle-forming method consisting in using hydrodynamic forces to focus a composite microjet formed by two concentric fluids and can be used in the encapsulation of fragile compounds of biological interest, from peptides and proteins to cells and micro-organisms.
Claims24
Procedure for the production of particles in the micro and nanometric range with encapsulated labile products characterized by that it is carried out with a Flow Focusing device, following by a solidification step to turn the drops into particles.
Dependencies are inferred from the claim text.