Two-Step Immunization Procedure Against Chlamydia Infection
OwnerRobert C. Brunham, Andrew D. Murdininventors
Life of this patent
Estimating the term…
Abstract
A host is immunized against infection by a strain of Chlamydia by initial administration of an attenuated bacteria harbouring a nucleic acid encoding a Chlamydia protein followed by administration of a Chlamydia protein in ISCOMs. This procedure enables a high level of protection to be achieved.
Claims12
-18. (canceled)
An attenuated strain of an auxotrophic bacterium harbouring a vector comprising a nucleic acid molecule encoding a major outer membrane protein (MOMP) of a strain of Chlamydia and a promoter operatively coupled to said nucleic acid molecule for expression of MOMP by cells of a host to which the strain is administered but not by said attenuated bacteria.
(canceled)
(canceled)
-40. (canceled)
Dependencies are inferred from the claim text.