Pharmaceutical compositions comprising a ph-dependent drug, a ph modifier and a retarding agent
OwnerAndrea Kramer, Angelika Ries +2inventors
InventorsAndrea Kramer, Angelika Ries, Stefanie Siepe, Barbara Lückel
Life of this patent
Estimating the term…
Abstract
The present invention concerns pharmaceutical compositions comprising a pH-dependent drug compound and a pH modifier.
Claims14
A pharmaceutical composition comprising a pH-dependent drug compound, a pH modifier and a retarding agent, wherein the drug release from the pharmaceutical composition is completed after a maximum dissolution time of between 1 and 4 hours.
A pharmaceutical composition comprising a pH dependent drug, fumaric acid and a cellulose derivative.
(canceled)
(canceled)
(canceled)
A method of reducing intra- and intersubject variability and improved bioavailability comprising the step of administering a pharmaceutical composition having a pH-dependent drug compound, a pH modifier and a retarding agent, wherein the drug release from the pharmaceutical composition is completed after a maximum dissolution time of between 1 and 4 hours.
The method of providing complete drug release from the pharmaceutical composition in the upper part of the intestinal tract, comprising the step of administering a pharmaceutical composition having a pH-dependent drug compound, a pH modifier and a retarding agent, wherein the drug release from the pharmaceutical composition is completed after a maximum dissolution time of between 1 and 4 hours.
Dependencies are inferred from the claim text.