Agent for use in the case of disorders of blood sugar metabolism, including diabetes
AssigneePro Natura Gesellschaft Fuer Gesunde Ernaehrung Mb
InventorsDaniel Henry Wyrobnik, Isaac Harry Wyrobnik
Life of this patent
Estimating the term…
Abstract
An agent for use in the case of disorders of blood sugar metabolism, including diabetes, is described, which reduces the glucose content of food and other substances with the help of 5-D-fructose dehydrogenase and glucose isomerase.
Claims20
1-230. (canceled)
A method of treating diabetes, reducing the effect of diabetes on a mammalian body, reducing the effect of D-glucose in a mammalian body, or reducing the effect of total glucose in a mammalian body, comprising administering to a mammalian subject in need of such treatment or reduction an efficacious amount of a combination of 5-D-fructose dehydrogenase and a glucose isomerase.
A kit comprising 5-D-fructose dehydrogenase and instructions explaining how to use said 5-D-fructose dehydrogenase in combination with a glucose isomerase to treat diabetes, to reduce the effects of diabetes on a mammalian body, to reduce the effects of glucose in a mammalian body or to reduce the effects of total glucose in a mammalian body.
A method for preparing a reduced total glucose foodstuff, comprising contacting a glucose-containing foodstuff or foodstuff precursor with 5-D-fructose dehydrogenase, a glucose isomerase and at least one enzyme that cleaves glucose or fructose from saccharide chains having at least two saccharide monomers, and completing any additional steps necessary to prepare the foodstuff, provided that said foodstuff precursor is not a dough and said foodstuff is not a dough or a baked foodstuff.
A process for preparing a 5-D-fructose dehydrogenase- and glucose isomerase-containing foodstuff, the process comprising adding to a foodstuff or foodstuff precursor 5-D-fructose dehydrogenase and a glucose isomerase, at least some of said 5-D-fructose dehydrogenase being in a form in which said 5-D-fructose dehydrogenase will be released in active form to act on fructose which is present in or released from said foodstuff after said foodstuff s ingested by a subject, and at least one of the following being true:
- (a) at least some of said glucose isomerase is in an active form in which said glucose isomerase can act on a substrate which is
- (i) present in or released from said foodstuff precursor or
- (ii) present in or released from said foodstuff before ingestion of said foodstuff, and
- (b) at least some of said glucose isomerase is present in said foodstuff in a form in which said glucose isomerase will be released in active form to act on a substrate which is present in or released from said foodstuff after ingestion of said foodstuff,
- and completing any additional steps necessary to prepare said foodstuff, whereby to obtain said 5-D-fructose dehydrogenase- and glucose isomerase-containing foodstuff.
Dependencies are inferred from the claim text.