Nasal Vaccine
AssigneeRiken
InventorsKen-ichiro Seino, Masaru Taniguchi, Takuya Tashiro, Ken-ichi Fuhshuku, Kenji Mori, Hideki Hasegawa
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Abstract
The present invention provides a nasal vaccine capable of intranasally inducing an effective immunity reaction. Specifically, the invention provides a nasal vaccine containing a compound having an NKT cell-activating action, particularly a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a compound represented by the formula (II): wherein each symbol is as defined in the specification, and an immunogen in an amount effective for stimulating an immune response.
Claims33
A nasal vaccine comprising a compound having an NKT cell activating action.
A nasal vaccine comprising a compound having an NKT cell-activating action and an immunogen in an amount effective for stimulating an immune response.
A method of inducing an intranasal immune response in a subject, which comprises administering (i) an immunogen in an amount effective for stimulating an immune response and (ii) an effective amount of a compound having an NKT cell-activating action.
A method of preparing a nasal vaccine, which method comprises the use of a compound having an NKT cell-activating action for the production of a nasal vaccine.
A method of preparing a nasal vaccine which method comprises the use of a compound having an NKT cell-activating action and an immunogen for the production of a nasal vaccine.
A commercial package comprising a pharmaceutical composition comprising a compound having an NKT cell-activating action, and a written matter stating that the composition can or should be used as a nasal vaccine.
A commercial package comprising a pharmaceutical composition comprising a compound having an NKT cell-activating action and an immunogen, and a written matter stating that the composition can or should be used as a nasal vaccine.
Dependencies are inferred from the claim text.