Immunogen platform
AssigneeTripep AB
InventorsMatti Sallberg, Jonas Soderholm, Lars Frelin
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Abstract
Aspects of the present invention relate to chimeric polypeptides including HCV NS3/4A sequences and T-cell epitopes. Embodiments include nucleic acids encoding the chimeric NS3/4A polypeptides, the encoded polypeptides, compositions containing said nucleic acids, compositions containing said chimeric polypeptides, as well as methods of making and using the aforementioned compositions including, but not limited to medicaments and vaccines.
Claims25
A nucleic acid encoding a hepatitis B virus core antigen (HBcAg) that is codon optimized for expression in humans.
A nucleic acid encoding a plurality of antigenic fragments of a hepatitis B virus core antigen (HBcAg) assembled in a non-naturally occurring order, wherein said nucleic acid is codon optimized for expression in humans.
Dependencies are inferred from the claim text.