US 2009/0214527 A1Published application

Combination Of Anti-Madcam Antibody And Antifibrotic Caspase Inhibitor To Treat Liver Fibrosis

OwnerGary Burgess, Roger Kerryinventors

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Abstract

The invention relates to a new combination of an anti-MAdCAM antibody with an anti-fibrotic agent, such as a protease inhibitor, preferably a caspase inhibitor. The invention also relates to pharmaceutical compositions comprising the combination of the invention, and the use of the combination for the treatment of liver fibrosis.

Claims12

Dependent claims

A combination of an anti-MAdCAM monoclonal antibody, or antigen binding portion thereof, and an anti-fibrotic agent.

Dependencies are inferred from the claim text.

Facts

Application: 11/995,204Filed 3 Jul 2006
Priority: 11 Jul 2005
Published: 27 Aug 2009
Term ends: Not estimatedThe source records don’t support an estimate.

Classification9 codes

A61K 45/06
Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00: mixtures of active ingredients without…
A61K 39/39541
Against materials from animals: against normal tissues, cells
A61P 1/16
Drugs for disorders of the alimentary tract or the digestive system: for liver or gallbladder disorders, e.g. hepatoprotective agents,…
A61P 29/00
Non-central analgesic, antipyretic or antiinflammatory agents

Family

Application60/698,561Us provisional application · filed 11 Jul 2005
US 2009/0214527 A1This patent

From the US filing history. Foreign family members aren’t listed.

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