Broad Spectrum Antiviral Compositions
AssigneeGovernment of the US, as represented by the Secretary, Department of Health and Human Services
InventorsGary J. Nabel, Jae Ouk Kim
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Abstract
The instant invention provides compositions and methods for the treatment of viral infections caused by enveloped viruses comprising phospholipase nucleic acid molecules or polypeptides, or fusion molecules comprising phospholipase molecules or functional fragments thereof.
Claims29
A polypeptide comprising a phospholipase polypeptide, or biologically active fragment thereof, and a viral binding polypeptide.
4-14. (canceled)
A polypeptide comprising phospholipase A2, or a biologically active fragment thereof, and DC-SIGN polypeptide connected by a peptide linker.
A polynucleotide encoding a polypeptide comprising a phospholipase polypeptide, or biologically active fragment thereof, and a viral binding polypeptide.
(canceled)
25-40. (canceled)
(canceled)
(canceled)
53-78. (canceled)
Dependencies are inferred from the claim text.