Method of treating preventing, inhibiting or reducing damage to cardiac tissue
AssigneeRegenerx Biopharmaceuticals, Inc.
InventorsDeepak Srivastava, Ildiko Bock-Marquette, Ankor Saxena, Allan L. Goldstein
Life of this patent
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Abstract
A method of treatment for treating, preventing, inhibiting or reducing damage to coronary tissue includes inducing at least one of a physiological function selected from: up-regulation of or increasing ILK activity in the coronary tissue, up-regulation of or increasing Akt activity in the coronary tissue, down-regulation of or reducing cardiomyocyte cell death in the coronary tissue and hibernation of cardiomyocytes in the coronary tissue. An induction agent capable of inducing such physiological function in a subject is administered to a subject in need of such treatment.
Claims26
A method of treatment for treating, preventing, inhibiting or reducing damage to coronary tissue comprising inducing at least one of a physiological function selected from:
- up-regulation of or increasing ILK activity in said coronary tissue, up-regulation of or increasing Akt activity in said coronary tissue, up-regulation of or increasing phosphatidylinositol 3-kinase (PI3K) activity in said coronary tissue, down-regulation of or reducing cardiomyocyte cell death in said coronary tissue and hibernation of cardiomyocytes in said coronary tissue, by administering to a subject in need of said treatment an induction agent capable of inducing said physiological function in said subject.
Dependencies are inferred from the claim text.