Method Of Using Mitotically Inactivated Stem Cells For Damaged Tissue Repair
OwnerRichard Burtinventor
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Abstract
The present invention is directed to the use of mitotically and/or lethally inactivated stem cells for the repair of damaged organs and/or tissues. Stem cells are mitotically and/or lethally inactivated and transplanted into damaged tissue. Any form of ex vivo inactivation of stem cells may be used such that the stem cells cannot undergo mitosis or cell division before in vivo application. Mitotically and/or lethally inactivated stem may be used to ameliorate numerous disease, injury, traumatic, ischemic, aging, and/or degenerative conditions in different types of organs and/or tissues.
Claims13
A method for repairing tissue comprising:
- mitotically and/or lethally inactivating stems cells;
- and
- transplanting the mitotically and/or lethally inactivated stem cells to the tissue.
A method of mitotically and/or lethally inactivating stem cells comprising:
- providing pluripotent stem cells;
- and
- inactivating the pluripotent stem cells with a method effective for inhibiting unlimited proliferation of the pluripotent stem cells and effective for inactivating adult stem cells such as umbilical cord blood to prevent their growth or persistence in a recipient.
Mitotically inactivated stem cell produced by a method comprising:
- providing pluripotent stem cells;
- and
- inactivating the pluripotent stem cells with a method effective for inhibiting unlimited proliferation of the pluripotent stem cells.
Dependencies are inferred from the claim text.