Stem cell therapy for the treatment of central nervous system disorders
OwnerNikolay Mironovinventor
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Abstract
The invention provides a method for treating CNS disorders by administering a neural stem cell composition and a mesenchymal stem cell composition on opposing sides of the blood brain barrier. The neural stem cell composition is administered to the central nervous system, while the mesenchymal stem cell composition is administered to the circulatory system, such as by intravenous injection. The method finds use in the treatment of degenerative GNS disorders, as well as traumatic CNS disorders such as stroke and spinal cord injury.
Claims20
A method for treating a CNS disorder in a subject having a blood brain barrier (BBB), said method comprising the steps of:
- administering on the neural side of said BBB a composition comprising a therapeutically effective amount of neural stem cells;
- and
- administering on the circulatory side of said BBB a composition comprising a therapeutically effective amount of mesenchymal stem cells.
Dependencies are inferred from the claim text.