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US 2009/0214473 A1Published application
Combination chaperonin 10 and beta-interferon therapy for multiple sclerosis
AssigneeThe University of Queensland of St. Lucia
InventorsHalle MORTON, Alice CAVANAGH
Life of this patent
Estimating the term…
Abstract
A method of treating multiple sclerosis (MS) is provided which includes the step of administering a pharmaceutically-effective amount of chaperonin 10 and IFN-beta. Also provided are pharmaceutical compositions and a kit for treating MS, which include chaperonin 10 and IFN-beta.
Claims24
1:
- A method of treating multiple sclerosis (MS), including the step of administering to an individual a pharmaceutically-effective amount of cpn10 and IFN-β.
2:
- The method of claim 1, when used as a treatment to prevent relapse of MS.
3:
- The method of claim 1, wherein IFN-β and cpn10 are administered together.
4:
- The method of claim 1, wherein IFN-β and cpn10 are administered separately.
5:
- The method of claim 3, wherein IFN-β and cpn10 are administered by injection.
6:
- The method of claim 4, wherein cpn10 is administered orally.
7:
- The method of claim 4, wherein IFN-β is administered by injection.
8:
- The method of claim 1, wherein the pharmaceutically effective amount of cpn10 and IFN-β comprises 5-60 mg of cpn10 .
9:
- The method of claim 8, wherein the pharmaceutically-effective amount of cpn10 and IFN-β comprises 10-30 mg of cpn10 .
10:
- The method of claim 1, wherein the pharmaceutically-effective amount of cpn10 and IFN-β comprises 1-10 Million International Units (MIU) of IFN-β.
11:
- The method of claim 10, wherein the pharmaceutically-effective amount of cpn10 and IFN-β comprises 4-6 MIU of IFN-β.
12:
- A pharmaceutical composition for treating MS, said composition comprising a pharmaceutically-effective amount of cpn10 and IFN-β and a pharmaceutically-acceptable carrier or diluent.
13:
- The composition of claim 12, wherein the pharmaceutically-effective amount of cpn10 and IFN-β comprises 5-60 mg of cpn10, or comprises 10-30 mg of cpn10 .
(canceled)
15:
- The composition of claim 12, wherein the pharmaceutically-effective amount of cpn10 and IFN-β comprises 1-10 MIU of IFN-β, or comprises 4-6 MIU of IFN-β.
(canceled)
17:
- A kit comprising a pharmaceutically-effective amount of cpn10 and IFN-β and a pharmaceutically-acceptable carrier or diluent.
18:
- The kit of claim 17, wherein said IFN-1 is in dehydrated form, which in use, is rehydrated by said pharmaceutically-acceptable carrier or diluent.
19:
- The kit of claim 18, wherein said cpn10 is in dehydrated form and in use, is rehydrated by said pharmaceutically-acceptable carrier or diluent.
20:
- The kit of claim 17, wherein said cpn10 is in tablet or capsule form.
21:
- The kit of claim 17, wherein the pharmaceutically-effective amount of cpn10 and IFN-β comprises 5-60 mg of cpn10, or comprises 10-30 mg of cpn10 .
(canceled)
23:
- The kit of claim 17, wherein the pharmaceutically-effective amount of cpn10 and IFN-β comprises 1-10 MIU of IFN-β, or comprises 4-6 MIU of IFN-β.
(canceled)
Dependencies are inferred from the claim text.