Micromachined Gas Chromatography Columns For Fast Separation of Organophosphonate and Organosulfur Compounds and Methods for Deactivating Same
AssigneeThe Regents University of Illinois
InventorsRichard I. Masel, Adarsh D. Radadia
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Abstract
Improved microcolumns and methods for producing microcolumns particularly suitable for use in gas chromatographs are disclosed. In particular, following deposition of the stationary phase coating, the microcolumns are subjected to a postcoating treatment with a molecule that binds to the active sites in the stationary phase column thereby eliminating or reducing loss of gas chromatograph performance associated with those active sites. The postcoating treatment molecule binds to the same active sites as the analytes of interest.
Claims24
A method for preparing a gas chromatograph (GC) column, said method comprising the steps of:
- deactivating a plurality of walls of a GC column;
- depositing a stationary phase in the GC column;
- and
- treating the GC column with a molecule such that the molecule binds to active sites in the stationary phase of the column.
A Gas chromatography (GC) column, comprising:
- a plurality of column walls each having a deactivated inner surface;
- a stationary phase layer deposited on the deactivated inner surface of said plurality of column walls;
- a plurality of binding sites in said stationary phase layer;
- and
- a post-coating molecule bound to at least one of said plurality of binding sites in said stationary phase layer.
Dependencies are inferred from the claim text.