Compositions and methods for preventing infection
AssigneeLa Jolla Biosciences LLC
InventorsGeorge A. Scheele, James E. Hildreth
Life of this patent
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Abstract
This invention relates to cholesterol-sequestering agents and methods of using cholesterol-sequestering agents to prevent infection. The compositions of the invention can be used to decontaminate skin and environmental surfaces that are contacted with microorganisms such as envelope viruses.
Claims45
A glove comprising an interior surface and an exterior surface, wherein the interior surface is coated with an amount of a cholesterol-sequestering agent effective to reduce or prevent dermal transmission of an envelope virus to an individual wearing the glove.
The kit of claim 11, wherein the kit comprises at least 10 of the gloves.
The kit of claim 11, wherein the kit comprises at least 50 of the gloves.
A composition comprising an absorbent material comprising a cholesterol-sequestering agent that prevents or reduces viral transmission, wherein the composition is formulated for dermal application to release an amount of the cholesterol-sequestering agent effective to reduce or prevent dermal transmission of an envelope virus to an individual when the composition is contacted to the skin of the individual.
A method of reducing or preventing viral transmission, the method comprising:
- selecting an individual engaged in an activity associated with an elevated risk of exposure to an envelope virus, wherein the activity is not a sexual or drug use-related activity;
- and
- contacting a skin surface of the individual with a composition comprising an amount of a cholesterol-sequestering agent effective to reduce or prevent dermal transmission of the envelope virus to the individual.
A method of treating an environmental surface, the method comprising:
- identifying a surface that has been exposed to blood or a blood product;
- and
- contacting the surface with a composition comprising an amount of a cholesterol-sequestering agent effective to reduce the amount of an envelope virus, if present, on the surface.
Dependencies are inferred from the claim text.