Method for Production of Radioisotope Preparations and Their Use in Life Science, Research, Medical Application and Industry

A method for producing a radioisotope-labelled bioconjugate wherein said method comprises the use of a radioisotope produced by a method comprising the following steps:

• (a) Activation of a target by a particle beam,
• (b) Separation of the isotope from the irradiated target,
• (c) Ionisation of the separated isotope,
• (d) Extraction from the ion source and acceleration of the ion beam,
• (e) Mass-separation, and
• (f) Collection of the isotope.

A method for direct labelling of a nanoparticle, macro-molecule, micro-sphere, macro-aggregate, ion exchange resin or other matrix used in a chromatographic system, comprising the following steps:

• (a) Obtaining a sample of an isotope, such as a commercially available isotope,
• (b) Introduction of said isotope into an oven from where said sample is fed into an ion source,
• (c) Ionisation of said isotope,
• (d) Extraction from the ion source and acceleration of the ion beam,
• (e) optionally, Mass-separation, and
• (f) Collection of the isotope by direct implanting of the radioactive ion beam into said nanoparticles, macro-molecules, micro-spheres, macro-aggregates, ion exchange resins or other matrices used in chromatographic systems.