Protein Adsorption Prevention Eye Lens Material And Method For Producing Same
AssigneesKazuhiko Ishihara, Shiseido Company, Ltd.
InventorsYukimitsu Suda, Kazuyuki Miyazawa
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Abstract
The present invention is a method of manufacturing an eye lens material having a process in which a phosphorylcholine group-containing chemical compound represented by the following formula (1) is reacted and covalently bonded onto the surface of an eye lens material wherein the chemical compound represented by the following formula (2) is reacted and covalently bonded through acetal bonding to the eye lens material having OH groups in water, an organic solvent, or a water/organic solvent mixture. The object of the present invention is to provide an eye lens material that prevents protein adsorption and a method of manufacturing thereof.
Claims8
A method of manufacturing an eye lens material having a process in which a phosphorylcholine group-containing chemical compound represented by the following formula (1) is reacted and covalently bonded onto the surface of an eye lens material wherein the chemical compound represented by the following formula (2) is reacted and covalently bonded through acetal bonding to the eye lens material having OH groups in water, an organic solvent, or a water/organic solvent mixture.
A method of manufacturing an eye lens material having a process in which a phosphorylcholine group-containing chemical compound represented by the following formula (1) is reacted and covalently bonded onto the surface of an eye lens material wherein OH groups are introduced to the surface of the eye lens material by means of a plasma treatment and then the chemical compound represented by the following formula (2) is reacted and covalently bonded through acetal bonding in water, an organic solvent, or a water/organic solvent mixture.
An eye lens material characteristically obtained with a method of manufacturing an eye lens material having a process in which a phosphorylcholine group-containing chemical compound represented by the following formula (1) is reacted and covalently bonded onto the surface of an eye lens material wherein the chemical compound represented by the following formula (2) is reacted and covalently bonded through acetal bonding to the eye lens material having OH groups in water, an organic solvent, or a water/organic solvent mixture.
An eye lens material characteristically obtained with a method of manufacturing an eye lens material having a process in which a phosphorylcholine group-containing chemical compound represented by the following formula (1) is reacted and covalently bonded onto the surface of an eye lens material wherein OH groups are introduced to the surface of the eye lens material by means of a plasma treatment and then the chemical compound represented by the following formula (2) is reacted and covalently bonded through acetal bonding in water, an organic solvent, or a water/organic solvent mixture.
A protein adsorption prevention method wherein protein adsorption on the eye lens material is prevented by means of an after-treatment in which the chemical compound represented by the following formula (2) is reacted and covalently bonded through acetal bonding to the eye lens material having OH groups in water, an organic solvent, or a water/organic solvent mixture.
Dependencies are inferred from the claim text.