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OwnerGeorge Cioca, Vasile Ionita-Manzatu +9inventors
InventorsGeorge Cioca, Vasile Ionita-Manzatu, Liliana George, Paolo U. Giacomoni, Andrew J. Bevacqua, Harvey Gedeon, Charles Craig Tadlock, Donald F. Collins, Thomas Mammone, Daniel H. Maes, Christina G. Fthenakis
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The present invention relates to a method of modulating a selected biological activity of a naturally occurring material having one or more biological activities in an extract of the naturally occurring material, the method comprising incubating the extract in a medium in the presence of an aerobically metabolizing microorganism, under suitable aerobic conditions, for a period of time sufficient to modulate the selected activity with respect to baseline activity of the unincubated extract. The invention also relates to the bioconverted material so prepared, and the use of same in cosmetic or pharmaceutical compositions.
A method of modulating a selected biological activity of a naturally occurring material having one or more biological activities in an extract of the naturally occurring material, the method comprising incubating the extract in a medium in the presence of an aerobically metabolizing microorganism, under suitable aerobic conditions, for a period of time sufficient to modulate the selected activity with respect to baseline activity of the unincubated extract, wherein the extract is selected from the group consisting of Centella asiatica extract, caffeine, resveratrol, white birch extract, spinach extract, Pterocarpus ulei extract, Aniba purchyriminor extract, plant essential oils, N-acetyl glucosamine, and mannose-6 phosphate.
A bioconverted material comprising resveratrol or a resveratrol-containing extract that has been incubated in a medium in the presence of an aerobically metabolizing microorganism, under suitable aerobic conditions, for a period of time sufficient to improve antioxidant activity with respect to unincubated resveratrol or resveratrol-containing extract.
Dependencies are inferred from the claim text.