Fast release solid formulation, preparation and use thereof
AssigneeSchering-Plough Animal Health Corporation
InventorsRobert D. Simmons, Serena Tongiani, Keith Alan Freehauf
Life of this patent
Estimating the term…
Abstract
The present invention relates to a chemically stable formulation of florfenicol, (and structurally related compounds) in compositions such as soluble blended powders, granules, fast-dissolving tablets or pellets suitable for rapid release of the drug in water, and to methods and kits for treating animals with aqueous compositions including florfenicol.
Claims28
A method for treating animals with florfenicol, comprising:
- a) providing a soluble solid dosage form based florfenicol composition comprising:
- i) from about 20 to about 60 wt % of florfenicol or a pharmaceutically acceptable salt thereof,
- ii) from about 0.5 to about 5.0 wt % of a water soluble binding agent, and
- iii) from about 40 to about 80 wt % of a filler;
- b) dissolving the composition of step a) in water;
- and
- c) administering the water containing the florfenicol to the animal in need thereof.
A method of treating an animal with florfenicol, comprising dissolving a soluble solid dosage form-based florfenicol composition comprising from about 20 to about 60 wt % of florfenicol or a pharmaceutically acceptable salt thereof, from about 0.5 to about 5.0 wt % of a water soluble binding agent, and from about 40 to about 80 wt % of a filler in a sufficient amount of water to provide a florfenicol concentration of from about 0.01 mg/mL to about 0.09 mg/mL, and administering the water containing the florfenicol to the animal in need thereof.
Dependencies are inferred from the claim text.