Back to results
US 2009/0156673 A1Published application
Anti-inflammatory actions of neuroprotectin d1/protectin d1 and it's natural stereoisomers
AssigneeThe Brigham and Women's Hospital, Inc. Corporate Sponsored Research and Licensing
InventorsCharles N. Serhan, Nicos A. Petasis, Bruce D. Levy
Life of this patent
Estimating the term…
Abstract
(Neuro)protectin D1 (1OR,17S-dihydroxy-docosa-4Z,7Z,11E,13E,15Z,19Z-hexaenoic acid) and 15,16-dehydro-PD1 and their derivatives are useful in the treatment of airway inflammation, especially asthma.
Claims26
A compound of formula (II):
- wherein R is a hydrogen atom, an alkyl group, or a pharmaceutically acceptable salt;
- and
- P1 and P2 are each, individually, a hydrogen atom or a protecting group, provided when P1 and P2 are both hydrogen atoms, then R is other than a hydrogen atom.
3-4. (canceled)
7-8. (canceled)
(canceled)
12-16. (canceled)
A compound of formula (IX):
- wherein R is a hydrogen atom, an alkyl group, or a pharmaceutically acceptable salt;
- and
- P1 and P2 are each, individually, a hydrogen atom or a protecting group.
(canceled)
22-28. (canceled)
Dependencies are inferred from the claim text.