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US 2009/0156670 A1Published application
Nonaqueous liquid parenteral aceclofenac formulation
AssigneeVenus Remedies Limited
InventorManu Chaudhary
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AssigneeVenus Remedies Limited
InventorManu Chaudhary
Estimating the term…
A nonaqueous liquid parenterally deliverable pharmaceutical formulation, and more particularly a nonaqueous liquid parenteral Aceclofenac formulation comprising the selective NSAID Aceclofenac, is disclosed. A process of preparing Aceclofenac formulation, the therapeutic dosage form and storage of dose, and the method of treating a subject having a condition or a disorder wherein treatment with NSAID is indicated, are also disclosed. Diclofenac formed by conversion of Aceclofenac is solubilized by the nonaqueous solubilizer(s), which are substantially inert with respect to such conversion. The composition has Aceclofenac salt stabilizing means for inhibiting precipitation of Aceclofenac. The compositions disclosed in the present invention are stable upon storage at room temperature and at refrigerated temperatures. Compositions disclosed in the present invention, whether ready-to-use or requiring dilution prior to administration, can be prepared by inexpensive processes disclosed herein.
A nonaqueous liquid parenteral Aceclofenac formulation, capable of pharmaceutical application, comprising an Aceclofenac component in a form of a non-water-soluble Aceclofenac salt, in a solubilized or dissolved form in a solvent liquid wherein said solvent liquid comprises:
A process for preparing a nonaqueous liquid parenteral Aceclofenac formulation for pharmaceutical application, which process comprises the steps of:
Dependencies are inferred from the claim text.