1-(1- (2-Ethoxyethyl)-3-Ethyl-7-(4-Methylpyridin-2-Ylamino) - 1H-Pyrazolo [4,3-D] Pyrimidin-5-YL) Piperidine-4-Carboxylic acid and salts thereof
AssigneePfizer Inc.
InventorMichael B. Tollefson
Life of this patent
Estimating the term…
Abstract
The present invention comprises 1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H-pyrazolo[4,3-d]pyrimidin-5-yl)piperidine-4-carboxylic acid and its salts. The invention further comprises pharmaceutical compositions, methods of treatment, and synthetic methods relating to 1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H-pyrazolo[4,3-d]pyrimidin-5-yl)piperidine-4-carboxylic acid and its salts.
Claims21
A compound, and pharmaceutically acceptable salts of the compound, having the structure:
A pharmaceutical composition comprising a compound, or a pharmaceutically acceptable salt of the compound, having the structure:
- a pharmaceutically-acceptable carrier.
A method of treating a condition in a subject, the method comprising administering to the subject a therapeutically-effective amount of a compound, or a pharmaceutically acceptable salt thereof, having the structure:
- wherein the condition is selected from the group consisting of a cardiovascular condition, a metabolic condition, a central nervous system condition, a pulmonary condition, sexual dysfunction, pain and renal dysfunction.
Use of a compound, or a pharmaceutically acceptable salt thereof, having the structure:
- in the manufacture of a medicament for the treatment of a condition selected from the group consisting of cardiovascular conditions, metabolic conditions, central nervous system conditions, pulmonary conditions, sexual dysfunction, pain and renal dysfunction.
A method of preparing a first compound having the structure:
- The method comprising contacting a second compound having the structure:
- with isonipecotic acid to provide the first compound.
Dependencies are inferred from the claim text.