Oral contraceptive spray
AssigneeN.V. Organon
InventorKees van der Voort Maarschalk
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Abstract
The subject invention provides a liquid contraceptive formulation for oral transmucosal administration. The formulation comprises etonogestrel, optionally together with ethinyl estradiol but does not contain a matrix former or a percutaneous absorption promoter, which is a hydroxy acid or a salt thereof.
Claims23
A liquid contraceptive formulation for oral mucosal administration comprising etonogestrel provided that the formulation does not contain a matrix former or a percutaneous absorption promoter which is a hydroxy acid or a salt thereof.
A contraceptive kit comprising a device comprising a liquid composition for oral mucosal administration by spraying, said composition comprising a contraceptively effective amount of etonogestrel for at least 7 daily metered doses.
A drug delivery system for female contraception comprising a device comprising a liquid composition for oral mucosal administration by spraying comprising at least 7 metered daily doses each comprising between 0.04 mg and 0.08 mg of etonogestrel.
A drug delivery system for female contraception comprising a device comprising a liquid composition for oral mucosal administration by spraying comprising at least 7 metered daily doses each comprising between 0.08 and 0.16 mg etonogestrel and between 0.015 and 0.03 mg of ethinyl estradiol.
Dependencies are inferred from the claim text.