MCP-1 Binding Nucleic Acids And Use Thereof
AssigneeNOXXON Pharma AG
InventorsWERNER PURSCHKE, FLORIAN JAROSCH, DIRK EULBERG, SVEN KLUSSMANN, KLAUS BUCHNER, CHRISTIAN MAASCH
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Abstract
The present invention is related to a nucleic acid molecule capable of binding to MCP-1, whereby the nucleic acid molecule is for use as a medicament for the treatment and/or prevention of a chronic disease or chronic disorder, preferably selected from the group consisting of chronic respiratory disease, chronic kidney disease and systemic lupus erythematosus.
Claims98
A nucleic acid molecule capable of binding to MCP-1, whereby the nucleic acid molecule is for use as a medicament for the treatment and/or prevention of a chronic disease or chronic disorder, preferably selected from the group consisting of chronic respiratory disease, chronic kidney disease and systemic lupus erythematosus.
A nucleic acid molecule capable of binding to MCP-1, whereby the nucleic acid molecule is for use as a diagnostic agent for the diagnosis of a chronic disease or chronic disorder, preferably selected from the group consisting of chronic respiratory disease, chronic kidney disease and systemic lupus erythematosus.
The nucleic acid molecule according to any of claims of 55 to 58, whereby the modification is coupled to the nucleic acid via a linker, whereby the linker is a linker or a biodegradable linker.
The nucleic acid molecule according to any of claims of 55 to 59, whereby the modification is coupled to the nucleic acid at its 5′-terminal nucleotide and/or its 3′-terminal nucleotide and/or to a nucleotide of the nucleic acid between the 5′-terminal nucleotide and the 3′-terminal nucleotide.
Dependencies are inferred from the claim text.