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AssigneePacific Arrow Limited
InventorsPui-Kwong Chan, May Sung Mak, Yun Wang
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This invention provides composition comprising a triterpenoidal saponin, triterpenoid, triterpenoidal compound or sapongenin, comprising at least two side groups selected from the group consisting of: angeloyl groups, tigloyl groups and senecioyl groups, wherein the side groups are attached to carbon 21, 22 or/and 28 of triterpenoidal saponin, triterpenoid, triterpenoidal compound or sapongenin backbone. This invention provides a composition for inhibiting tumor cell growth, comprising an appropriate amount of a triterpenoidal saponin, triterpenoid, triterpenoidal compound or sapongenin, wherein the triterpenoidal saponin, triterpenoid, triterpenoidal compound or sapongenin comprises any two side groups selected from the group consisting of: angeloyl groups, tigloyl groups and senecioyl groups, wherein the side groups are attached to carbon 21, 22 or/and 28 of triterpenoidal saponin, triterpenoid, triterpenoidal compound or sapongenin backbone.
1-371. (canceled)
A method for inhibiting ovarian or skin cancer cell growth in a subject comprising administering to the subject an effective amount of a compound, or its salt or ester thereof, selected from formula,
A method for inhibiting ovarian or skin cancer cell growth in a subject, by administering to the subject an effective amount of a compound, or its salt or ester thereof, selected from formula,
The method of claim 371, wherein R4 represents CH2OR6, wherein R6 is acyl, wherein the acyl include acetyl.
The method of claim 371, wherein the compound has at least two acyl groups;
The method of claim 371, wherein the cancer cells include ovarian and skin cancer cell growth in a subject, comprising administering to the subject an effective amount of a compound, or its salt or ester thereof, wherein the compound is (ACH—Y) having the following structure:
Dependencies are inferred from the claim text.