Biodegradable nanoparticle having t-cell recognizable epitope peptide immobilized thereon or encapsulated therein
OwnerMitsuru Akashi, Koichi Ikizawainventors
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Abstract
A biodegradable nanoparticle having a T cell recognizable epitope peptide immobilized thereon or encapsulated therein of the present invention is usable as a safe and effective immunotherapeutic agent, and is useful as an immunotherapeutic agent for treating, for example, pollinosis, year-round nasal allergic disease and seasonal nasal allergic disease.
Claims15
A biodegradable nanoparticle having a cedar pollen T cell recognizable epitope peptide immobilized thereon or encapsulated therein.
(canceled)
5-7. (canceled)
An immunotherapeutic agent according to 8 for treating and/or preventing cedar pollinosis.
A method for preparing an immunotherapeutic agent for treating and/or preventing cedar pollinosis comprising the step of combining an immunotherapeutically effective amount of a biodegradable nanoparticle having a cedar pollen T cell recognizable epitope peptide immobilized thereon or encapsulated therein with a pharmaceutically effective carrier or excipient.
(canceled)
An immunotherapy comprising administering to a mammal an effective amount of a biodegradable nanoparticle having a T cell recognizable epitope peptide immobilized thereon or encapsulated therein.
Dependencies are inferred from the claim text.