4-alkoxy-cyclohexane-1-amino-carboxylic esters and processes for their preparation
AssigneeBayer CropScience AG
InventorsThomas Himmler, Reiner Fischer, Bernd Gallenkamp, Hans-Joachim Knops, Lubbertus Mulder
Life of this patent
Estimating the term…
Abstract
The invention relates to novel 4-alkoxy-cyclohexane-1-amino-carboxylic esters of the formula (IV) in which R1 and R2 are as defined in the description, to intermediates and processes for their preparation and to their use as intermediates in the synthesis of insecticidal, acaricidal and herbicidal compounds or pharmaceutically active compounds.
Claims12
Compounds of the formulae (IV-a) and (IV-b)
- in which
- R1 represents OR3,
- R2 represents alkyl and
- R3 represents alkyl.
Compounds of the formula (III)
- in which
- R1 is as defined above.
Compounds of the formula (III-a)
- in which
- R1 is as defined above.
Compounds of the formula (III-b)
- in which
- R1 is as defined above.
Process for preparing compounds of the formula (III),
- in which
- R1 is as defined above,
- characterized in that compounds of the formula (II)
- in which
- R1 is as defined above
- are reacted with ammonium carbonate and alkali metal cyanides or trimethylsilyl cyanide (TMSCN) in the solvent water.
Process for preparing compounds of the formula (III-a),
- in which
- R1 is as defined above,
- characterized in that compounds of the formula (II)
- in which
- R1 is as defined above
- are reacted with an alkali metal cyanide and ammonium carbonate in water.
Process for isolating compounds of the formula (III-a)
- in which
- R1 is as defined above,
- characterized in that compounds of the formula (III) are treated with aqueous ammonia.
Compounds of the general formula (I)
- in which
- R1 represents OR3,
- where
- R3 represents alkyl.
Dependencies are inferred from the claim text.