Horse:Human Chimeric Antibodies
AssigneeThe Florida International University Board of Trustees
InventorsJuan C. Almagro, Alejandro Alagon-Cano, Jorge P. Solis, Sylvia L. Smith, Alvaro Velandia
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Abstract
The present invention provides a plurality of chimeric single chain variable region (scFv) antibodies. The chimeric scFv antibodies individually comprise variable regions from both horse and non-horse antibodies. Methods of making and using the plurality are also provided.
Claims37
A plurality of chimeric single chain Fv (scFv) antibodies comprising at least two or more chimeric scFv antibodies that are immunospecific for different/distinct epitopes, said chimeric scFv antibodies individually comprising a horse Fv domain and a non-horse Fv domain.
Dependencies are inferred from the claim text.