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US 2009/0155837 A1Published application
Two-photon fluorescent probes for acidic vesicles in live cells and tissue and method of imaging acidic vesicles in live cells and tissue using the same
AssigneeKorea University Industrial & Academic Collaboration Foundation
InventorBong-Rae Cho
Life of this patent
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Abstract
Provided are two-photon fluorescent probes for imaging acidic vesicles in live cells and tissue. The probes are represented by The probes can selectively bind to vesicles in cytosol to emit two-photon excited fluorescence with high intensity. Therefore, the use of the probes enables effective imaging of acidic vesicles. Further provided is a method for imaging acidic vesicles in live cells and tissue using the probes.
Claims8
A two-photon fluorescent probe for imaging acidic vesicles in live cells and tissue, represented by Formula 1:
- wherein R1 is (CH3)2NCH2CH2— or
- (R2 is a hydrogen atom or a methoxy group).
Dependencies are inferred from the claim text.