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AssigneeNational University Corporation Nagoya
InventorsAtsumi Nitta, Minae Niwa, Toshitaka Nabeshima
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Disclosed is useful means for the therapy or diagnosis of a mental disorder. A method for screening for a compound which is effective for a mental disorder, comprising the steps of (1) providing a cell capable of expressing a gene (target gene) selected from the group consisting of a gene having the nucleotide sequence depicted in SEQ ID NO:1, a gene having the nucleotide sequence depicted in SEQ ID NO:2, a gene having the nucleotide sequence depicted in SEQ ID NO:3 and genes homologous to these genes; (2) exposing the cell to a compound to be tested; (3) determining the amount of a product of the target gene expressed in the cell after the exposure to the compound; and (4) determining the change in amount of the product of the target gene under the influence of exposure to the compound.
A method for screening a compound that is effective for a mental disorder, the method comprising the steps of:
A method for screening a compound that is effective for a mental disorder, the method comprising the steps of:
A method for obtaining information for diagnosis of a mental disorder, the method comprising the steps of:
An antipsychotic drug comprising a compound for increasing the expression level in the target tissue of a gene selected from the group consisting of a gene having a base sequence of SEQ ID NO.:
A reagent for studying a mental disorder, comprising an isolated nucleic acid having the base sequence of any of SEQ ID NOs.:
An expression vector for treating or studying a mental disorder, which comprises a nucleic acid encoding the amino acid sequence of any of SEQ ID NOs.:
An antibody for treating, diagnosing, or studying a mental disorder, which is an isolated antibody to protein having the amino acid sequence of any of SEQ ID NOs.:
Dependencies are inferred from the claim text.