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US 2009/0155121 A1Published application
Method for Irradiating Thrombocyte Concentrates in Flexible Containers With Ultra-Violet Light
AssigneesForschungsgemeinschaft der DRK Blutspendedienste e.V., Maco Pharma
InventorsHarald Mohr, Wolfram H. Walker
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Abstract
The invention relates to a method for inactivating pathogens such as bacteria and viruses and/or leucocytes in thrombocyte concentrations by irradiation in flexible containers with ultra-violet light using agitation. The blood product is packaged in a flexible bag to permit the intermixing of the fluid by agitation (tilting, rotation, translation). This is also promoted by the filling of the bag to a maximum 30% of the filling capacity.
Claims25
A method for inactivating pathogens and/or leucocytes in platelet concentrates (PCs) comprising the steps:
- providing PCs obtained from donor blood and/or by mechanical apheresis,
- exposing the PCs to irradiation with ultraviolet (UV) light,
- in which the PCs consist of a plurality of units which are able to be handled individually and stored separately, and
- the PC units are each placed in flexible, UV-penetrable flat exposure bags, characterized in that
- the exposure bags are filled to less than 30% of the maximum filling volume of the exposure bags and
- the exposure bags are moved during the irradiation with UV light so that the contents of
- the exposure bags are circulated and zones of changing layer thicknesses are formed by the movement.
4 more elements
Dependencies are inferred from the claim text.