Magnetic separation of fine particles from compositions
AssigneesBaxter International Inc., Baxter Healthcare S.A.
InventorsJames E. Kipp, Joseph Chung Tak Wong, Jane O. Werling
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Abstract
The disclosure describes apparatuses and methods of use that may be used to remove material with magnetic properties from compositions, particularly pharmaceutical compositions. The apparatuses provide a conduit or column in which a magnetic field exists and through which a composition flows. Magnetic material in the composition is substantially reduced after flowing through the conduit or column.
Claims43
An apparatus for removing material with magnetic properties from a composition, comprising:
- a conduit wherein said conduit has first and second ends and wherein said conduit defines an interior volume;
- an magnetic arrangement of at least one permanent magnet that defines a space, and said conduit lies at least partially within said space such that a magnetic field is generated within at least a portion of said interior volume;
- and
- wherein said composition flows through said conduit and is subject to said magnetic field.
An apparatus for removing material with magnetic properties from a composition, comprising:
- a conduit wherein said conduit has first and second ends and wherein said conduit defines an interior volume;
- an arrangement of magnets selected from the group consisting split and whole ring magnets, such that said arrangement forms at least one double Halbach opposed array magnetic field;
- and
- said conduit lies at least partially within the space between formed by said double Halbach opposed array and said composition is subject to said magnetic field.
An apparatus for removing material with magnetic properties from a composition, comprising:
- a column wherein said column has first and second open ends and wherein said conduit defines an interior volume;
- an arrangement of beads of permanent magnets such that a magnetic field is generated within at least a portion of said interior volume;
- and
- said composition flows through said column and through said magnetic field.
A system for removing material with magnetic properties from a composition, comprising:
- at least one device used to produce a composition;
- a conduit, said conduit having first and second ends, one end of said conduit being adapted to receive said composition from said device;
- and
- an arrangement of at least one magnet such that a magnetic field is generated within at least a portion of said interior volume of said conduit, whereby material with magnetic properties is removed from said composition.
A method to produce a composition substantially free of material with magnetic properties comprising the steps of:
- a) providing a composition containing material with magnetic properties;
- b) passing said composition through a conduit;
- c) herein at least a portion of said conduit is exposed to a magnetic field generated by an arrangement of at least one permanent magnet;
- and
- d) collecting said pharmaceutical composition after passage through said conduit.
An apparatus for removing material with magnetic properties from a composition, comprising:
- a conduit wherein said conduit has first and second ends and wherein said conduit defines an interior volume;
- an arrangement of permanent magnets that generates a magnetic field;
- and
- said conduit is adjacent to or in contact with the external surface of said arrangement of magnets and said composition is subject to said magnetic field.
Dependencies are inferred from the claim text.