Biocompatible foams, systems, and methods
AssigneeSurModics, Inc.
InventorsEmily R. Rolfes, Stephen J. Chudzik, Pamela J. Reed
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Abstract
Biocompatible foams having excellent physical and chemical properties are described. The biocompatible foams can be formed in situ or applied as a pre-formed foam for the treatment of tissue. The invention provides biocompatible degradable foams formed with a poly-α(1→4)glucopyranose macromer. The invention also provides biostable foams formed with a poly(alkylene oxide) macromer.
Claims22
A system for forming a biocompatible biodegradable foam comprising:
- a covalently crosslinkable polymer comprising poly-α(1→4)glucopyranose and pendent polymerizable groups;
- a polymerization initiator;
- and
- a gas-producing component.
A method for forming a biocompatible biodegradable foam comprising a step of:
- providing a composition comprising a covalently crosslinkable polymer comprising poly-α(1→4)glucopyranose and pendent polymerizable groups, a polymerization initiator, and a gas-producing component, wherein the a gas-producing component reacts to produce gas and the polymerization initiator is activated to cause polymerization and formation of a foam.
A biocompatible biodegradable foam comprising poly-α(1→4)glucopyranose segments covalently crosslinked via polymerized groups.
Dependencies are inferred from the claim text.