Methods for Antibody Library Screening
AssigneeAffitech AS
InventorsMarike Josee Janneke Gertrud Stassar, Herald Reiersen
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Abstract
The present invention provides an improved method of screening a library of molecules to identify or select one or more members thereof which are candidate binding partners for one or more target entities: (a) contacting an expression library with one or more target entities; (b) subjecting said target entities to at least one washing step; (c) separating target entities which have become bound to one or more members of the expression library from unbound members of the expression library by separation through an organic phase, thereby separating candidate binding partners for said target entities from other library members.
Claims42
A method of screening a library of molecules to identify or select one or more members thereof which are candidate binding partners for one or more target entities comprising:
- (a) contacting an expression library with one or more target entities;
- (b) subjecting said target entities to at least one washing step;
- (c) separating target entities which have become bound to one or more members of the expression library from unbound members of the expression library by separation through an organic phase, thereby separating candidate binding partners for said target entities from other library members.
Dependencies are inferred from the claim text.