Assay
OwnerIvan Mikhailovich PETYAEVinventor
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Abstract
A method for determining the risk of an individual of suffering from inflammation, opportunistic infection or disruption of immunoglobulin metabolism, comprising (a) determining the level of fragmentation or modification of Fc function of immunoglobulins in a sample taken from the individual and (b) determining thereby the risk of inflammation, impaired immune response or opportunistic infection. The invention also provides the use of a trypsin inhibitor in the manufacture of a medicament for use in the treatment or prevention of a disorder associated with elevated trypsin activity which is correlated with IgG fragmentation or modification.
Claims15
A method for the treatment of a patient who has suffered or is suffering from a disorder associated with elevated trypsin activity which is correlated with IgG fragmentation or modification, which method comprises the step of administering to the patient a therapeutically effective amount of a trypsin inhibitor.
A method for determining the risk of an individual of suffering from inflammation, opportunistic infection or disruption of immunoglobulin metabolism, comprising
- (a) determining the level of fragmentation or modification of Fc function of immunoglobulins in a sample taken from the individual and
- (b) determining thereby the risk of inflammation, impaired immune response or opportunistic infection.
A kit for determining the risk of an individual of suffering from inflammation, opportunistic infection or disruption of immunoglobulin metabolism, which comprises means for determining the level of fragmentation or modification of Fc function of immunoglobulins in a sample taken from the individual.
Dependencies are inferred from the claim text.