Involvement of a Novel Nuclear-Encoded Mitochondrial Poly(A) Polymerase PAPD1 in Extreme Obesity-Related Phenotypes in Mammals
OwnerZhihua Jiang, Jennifer J. Michal +1inventors
InventorsZhihua Jiang, Jennifer J. Michal, Qianjun Xiao
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Abstract
Aspects of the present invention also provide novel compositions and methods based on novel PAPD1 single nucleotide polymorphisms selected from the group consisting of AAFC02034082.1:g.9224G>A, g.9330A>C, g.9367G>C, g.9419A>C, g.9435T>G, g.9409[(G)4]+[(G)5], g.10084T>C, g.10228G>T, c.10326C>T and c.10364A>G, which may provide novel markers for intramuscular fat deposition. Additional aspects provide for novel methods which may comprise marker-assisted selection or marker-assisted management to improve intramuscular fat deposition in cattle.
Claims18
A method for identifying an animal having desirable intramuscular fat deposition, as compared to the general population of animals of that species, comprising determining the presence of one or more single nucleotide polymorphisms in a PAPD1 gene of the animal, wherein the single nucleotide polymorphism is indicative of intramuscular fat deposition.
An interactive computer-assisted method for tracking the rearing of livestock bovines comprising, using a computer system comprising a programmed computer comprising a processor, a data storage system, an input device, an output device, and an interactive device, the steps of:
- (a) inputting into the programmed computer through the input device data comprising a breeding history of a bovine or herd of bovines and a genotype of a bovine;
- correlating a physical characteristic predicted by the genotype using the processor and the data storage system, (b) inputting into the programmed computer through the input device data comprising a veterinary history of a bovine or herd of bovines, (c) correlating the veterinary data with the breeding history of the bovine or herd of bovines using the processor and the data storage system, and (d) outputting to the output device the breeding history, the veterinary history of the bovine or herd of bovines and the physical characteristic correlated to the genotype for a bovine or population of bovines, wherein the physical characteristic is desirable beef marbling, subcutaneous fat, or a combination thereof, as compared to the general population of bovines, and the genotype is a single nucleotide polymorphism in a PAPD1 gene.
Dependencies are inferred from the claim text.