Back to results
US 2009/0023931 A1Published application
Alanine racemase chiral binaphthol derivative with powerful hydrogen bond donor, and optical resolution and optical transformation methods using the same
AssigneeEwha University-Industry Collaboration Foundation
InventorsKim Kwan Mook, Tang Lijun
Life of this patent
Estimating the term…
Abstract
Disclosed is an alanine racemase chiral binaphthol derivative having the ability to recognize amino alcohols selectively on the basis of chirality and transform amino acids from an L-form into a D-form. Methods for the optical resolution of amino acid or amino alcohol and for the optical transformation of D- and L-forms of amino acids using the binaphthol derivative are also provided.
Claims6
A binaphthol derivative, having a chemical structure below:
- and being selected from a group consisting of compounds represented by Formulas I to VI below:
- in Formulas I to VI, R1 to R8 are each i) linear or branched alkyl substitutable with —OH, hydrogen or halogen, ii) cyclic alkyl, alkenyl or alkynyl substitutable with —OH or halogen, or iii) aryl substitutable with —OH or halogen.
Dependencies are inferred from the claim text.