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US 2009/0023894 A1Published application
Neutralizing Antibody Against HGF
AssigneeNational Cancer Center
InventorsJunho Chung, Youngmi Hur
Life of this patent
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Abstract
The neutralizing antibody against HGF binding to the inventive neutralizable epitope of HGF is capable of neutralizing HGF as a single agent, and can be effectively used for preventing and treating intractable diseases and cancers that are caused by binding of HGF to its receptor Met.
Claims3
A polypeptide neutralizing hepatocyte growth factor (HGF) which has the amino acid sequence of SEQ ID NO:
- 32 wherein said polypeptide inhibits the binding of HGF to cMet.
2-10. (canceled)
A polypeptide neutralizing hepatocyte growth factor (HGF) which has the amino acid sequence of SEQ ID NO:
- 33 wherein said polypeptide inhibits the binding of HGF to cMet.
Dependencies are inferred from the claim text.