Use of an Artificial Sweetener to Enhance Absorption of Nicotine
OwnerAnders Axelssoninventor
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Abstract
The present invention relates to increased absorption of nicotine over the prior art. In particular the absorption of nicotine is enhanced after administration of a composition containing nicotine and a sweetener such as an artificial sweetener like saccharin to the oral mucosa in the form of a spray.
Claims37
A method of enhancing an absorption of a nicotine or a salt, complex, derivative or solvate thereof, by a subject comprising the step of administering a sufficient amount of an artificial sweetener comprising a sulfonamide group, or a salt, complex, derivative or solvate thereof, to enhance the absorption of the nicotine, or a salt, complex, derivative or solvate thereof.
A composition comprising an artificial sweetener comprising a sulfonamide group, or a salt, complex, derivative or solvate thereof, and nicotine or a salt, complex, derivative or solvate thereof, wherein the artificial sweetener and the nicotine is present in a weight ratio of from at least about 0.2, and the weight ratio is calculated as the ratio between the artificial sweetener in the form of its sodium salt and nicotine in the form of the free base nicotine.
Dependencies are inferred from the claim text.