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US 2009/0023802 A1Published application
Benzochromene Derivatives
AssigneeMerck Patent GmbH
InventorsAndreas Taugerbeck, Melanie Klasen-Memmer
Life of this patent
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Abstract
The present invention relates to benzochromene derivatives of the formula I where the various parameters have the meaning indicated in the text, and to liquid-crystal media which comprise these compounds, and to the use of the media in electro-optical displays, in particular in VAN-LCDs, and to the use of the compounds and physiologically acceptable derivatives thereof as therapeutic active ingredients.
Claims18
Compound of the formula I
- in which
- Y denotes —CO—, —CS—, —CH2— or —CF2—,
- L denotes H, halogen or —CF3,
- each, independently of one another and, if present more than once, also these independently of one another, denote
- (a) a trans-1,4-cyclohexylene radical, in which, in addition, one or two non-adjacent CH2 groups may be replaced by —O—and/or —S—,
- (b) a 1,4-cyclohexenylene radical,
- (c) a 1,4-phenylene radical, in which, in addition, one or two non-adjacent CH groups may be replaced by N, or
- (d) naphthalene-2,6-diyl, decahydronaphthalene-2,6-diyl and 1,2,3,4-tetrahydronaphthalene-2,6-diyl,
- (e) a radical selected from the group 1,4-bicyclo[2.2.2]octylene, 1,3-bicyclo[1.1.1]pentylene and spiro[3.3]heptane-2,6-diyl,
- where in
- (a) and (b), one or more —CH2— groups, independently of one another, may each be replaced by a —CHF— or —CF2— group, and in
- (c) and (d), one or more —CH═ groups, independently of one another, may each be replaced by a —CF═, —C(CN)═, —C(CH3)═, —C(CH2F)═, —C(CHF2)═, —C(O—CH3)═, —C(O—CHF2)═ or —C(O—CF3)=group, preferably a —CF═ group, and preferably denote
- denotes a 1,4-trans-cyclohexane-1,2,4-triyl radical, in which, in addition, one or two non-adjacent CH2 groups may be replaced by —O— and/or —S—, and one or more —CH2— groups, in each case independently of one another, may each be replaced by a —CHF— or —CF2— group, and the —CH< group may be replaced by a —CF< group, and which may optionally contain one or two C—C double bonds, where, in this case, one or more —CH═ groups, independently of one another, may each be replaced by a —CF═, —C(CN)═, —C(CH3)═, —C(CH2F)═, —C(CHF2)═, —C(O—CH3)═, —C(O—CHF2)═ or —C(O—CF3)═ group, preferably a —CF═ group,
- R1 and R2 each, independently of one another, denote H, halogen, —CN, —SCN, —SF5, —CF3, —CHF2, —CH2F, —OCF3, —OCHF2, an alkyl group having 1 to 15 C atoms which is monosubstituted by CN or CF3 or at least monosubstituted by halogen, where, in addition, one or more CH2 groups, in each case independently of one another, may be replaced by —O—, —S—, —CH═CH—, —CF═CF—, —CF═CH—, —CH═CF—,
- —CO—, —CO—O—, —O—CO— or —O—CO—O— in such a way that neither O nor S atoms are linked directly to one another,
- Z1 and Z2 each, independently of one another, denote —CH2—CH2—, —CF2—CF2—, —CF2—CH2—, —CH2—CF2—, —CH═CH—, —CF═CF—, —CF═CH—, —CH═CF—, —C≡C—, —COO—, —OCO—, —CH2O—, —OCH2—, —CF2O—, —OCF2—, or a combination of two of these groups, where no two O atoms are bonded to one another, and
- n and m each denote 0, 1 or 2, where
- n+m denotes 0, 1, 2 or 3.
15 more elements
Dependencies are inferred from the claim text.