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US 2009/0023776 A1Published application
Farnesyl protein transferase inhibitor combinations with antiestrogen agents
OwnerDavid William Endinventor
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Abstract
The present invention is concerned with combinations of a farnesyl transferase inhibitor and an antiestrogen agent for inhibiting the growth of tumor cells, useful in the treatment of cancer.
Claims3
1-33. (canceled)
A combination of tamoxifen and a farnesyl transferase inhibitor wherein the farnesyl transferase inhibitor is (+)-6-[amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chloro-phenyl)-1-methyl-2(1H)-quinolinone;
- or a pharmaceutically acceptable acid addition salt thereof.
Dependencies are inferred from the claim text.