Modified release famciclovir pharmaceutical compositions
OwnerWai Yip Lee, Shoufeng Liinventors
Life of this patent
Estimating the term…
Abstract
A modified release pharmaceutical composition of famciclovir contains at least 60% by weight famciclovir with at least 5% by weight of a release retardant. Particularly useful as a release retardant include polymers, especially a mixture of polyvinyl acetate and polyvinylpyrrolidone. A method of making such pharmaceutical compositions using a extruder and a granulation method is particularly useful.
Claims17
A pharmaceutical composition comprising famciclovir and a release retardant wherein said composition comprises at least 5% by weight release retardant.
A method of making a modified release pharmaceutical composition comprising the step of granulating famciclovir with a release retardant in a extruder while heating to a temperature below 104° C. to form granules.
A method of making a modified release pharmaceutical composition comprising the step of granulating famciclovir with a polymer in a extruder while heating to a temperature between the Tg of said polymer and below the melting range of famciclovir to form granules.
Dependencies are inferred from the claim text.