Method of Treating Organophosphorous Poisoning
AssigneeUniversity of Maryland, Baltimore
InventorsEdson X. Albuquerque, Michael Adler, Edna F.R. Pereira
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Abstract
The present invention is directed to various methods for treating organophosphorus poisoning in an animal that is at risk of exposure to an organophosphorus compound or preventing organophosphorus poisoning in an animal that has been exposed to an organophosphorus compound, by administering a therapeutically effective amount of galantamine or a salt thereof, or a biologically active analog, derivative, fragment or variant thereof.
Claims41
A method for treating organophosphorus poisoning in an animal that is at risk of exposure to an organophosphorus compound or preventing organophosphorus poisoning in an animal that has been exposed to an organophosphorus compound, comprising administering a therapeutically effective amount of galantamine or a salt thereof, or a biologically active analog, derivative, fragment or variant thereof.
A method for preventing organophosphorus poisoning in an animal that is at risk of repeated exposure to sublethal doses of an organophosphorus compound, comprising administering a therapeutically effective amount of galantamine or a salt thereof, or a biologically active analog, derivative, fragment or variant thereof up to three times per day for a duration of the risk.
A pharmaceutical composition comprising galantamine or a salt thereof, or a biologically active analog, derivative, fragment or variant thereof and atropine or a salt thereof, or a biologically active analog, derivative, fragment or variant thereof.
A method of treating or preventing the loss of cognitive function or neuronal degeneration in an animal after organophosphorus poisoning, comprising administering a therapeutically effective amount of galantamine or a salt thereof, or a biologically active analog, derivative, fragment or variant thereof.
A method of treating or preventing intermediate syndrome in an animal that is at risk of developing it, comprising administering a therapeutically effective amount of galantamine or a salt thereof, or a biologically active analog, derivative, fragment or variant thereof.
Dependencies are inferred from the claim text.