Cyclic Antimicrobial Peptides

Use of a cyclic peptide, or variant thereof, comprising amino acids according to the formula I:

• ((X)1(Y)m)n (I)
• wherein 1 and m are integers from 0 to 10 such that both 1 and m are not 0, n is an integer from 1 to 10, X and Y, which may be the same or different, are an amino acid selected from the group consisting of cationic amino acids, in the manufacture of a medicament for the treatment of a microbial infection.

Use of a cyclic peptide, or variant thereof, comprising amino acids according to the formula I:

• ((X)1(Y)m)n (I)
• wherein 1 and m are integers from 0 to 10 such that both 1 and m are not 0, n is an integer from 1 to 10, X and Y, which may be the same or different, are an amino acid selected from the group consisting of cationic amino acids, in the manufacture of a medicament for the treatment of a wound.

A method of treating or preventing a microbial infection in a subject the method comprising administering to said subject a therapeutically effective amount of a cyclic peptide, or variant thereof, comprising amino acids according to the formula I:

• ((X)1(Y)m)n (I)
• wherein 1 and m are integers from 0 to 10 such that both 1 and m are not 0, n is an integer from 1 to 10, X and Y, which may be the same or different, are an amino acid selected from the group consisting of cationic amino acids.